Impulse Oscillometry: state of the art lung function machine

A2002581

Respiratory disease affects one in five people and is a leading cause of global morbidity and mortality. Chronic obstructive airways diseases encompass conditions characterised by expiratory airflow limitation, exertional dyspnoea, activity limitation and impaired quality of life. The most common conditions include chronic obstructive pulmonary disease (COPD), asthma, bronchiectasis, cystic fibrosis and primary ciliary dyskinesia.

In recent years, there has been concerted effort in the scientific and respiratory medicine community to improve the diagnosis and management of chronic obstructive airways diseases using personalised or precision medicine i.e. tailoring therapies and interventions according to specific “treatable traits”.  To date, however, research in this setting has primarily focussed on people with COPD and asthma, with limited studies in other forms of chronic obstructive airways diseases.

The aim of this doctoral research programme is therefore two-fold; first, to compare pulmonary physiology i.e. large and small airway involvement and other effects on the body, across the full range of chronic obstructive airways diseases. Secondly, to determine how disease-specific treatable traits associate with physical activity and health-related quality of life.

Lead Researcher	Lauren Lear Clinical Service Manager
Host Organisation	Cardio-Respiratory Leeds Teaching Hospitals NHS Trust
Grant Amount	£16,476.37
Start Date	07/07/2023
Estimated Duration	18 months
Impact Areas	Innovation & Health Technologies
Tags/key notes	Respiratory